Detection of nanoparticles in tissues

Detection of nanoparticles in tissues

Detection of nanoparticles in tissues

Quantitative detection of nanoparticles in biological matrices is difficult, not least due to the large surface area of nanomaterials and the associated high reactivity. The small size of the materials contributes to their increased mobility and bioavailability. The aim of detecting nanoparticles in tissues using various techniques is to determine organ contamination as well as to detect and visualise the inhomogeneous distribution of nanoparticles and individual contaminated cells in the tissue. Research is constantly being conducted to improve the detection limit and the resolution of the detection methods.

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Regional experts:

Prof. Dr. Uwe Karst

Institute for Pharmaceutical and Medicinal Chemistry, WWU Münster

Dr. Fabian Herrmann

IPBP Institute for Pharmaceutical Biology and Phytochemistry, WWU Münster

Prof. Dr Bart Jan Ravoo

SoN (Center for Soft Nanoscience), WWU Münster

  • Organic and supramolecular chemistry, molecular monolayers, nanotechnology

Dr. Jürgen Schnekenburger

Head of Biomedical Technology Centre, WWU Münster

  • Label-free imaging, nanotoxicology, digital image analysis/diagnostics, industrial applications

Best practices/applications/signals:

IBE R&D gGmbH

  • Biological-toxicological evaluation of micro- and nanoscale particles, research in the framework of publicly funded projects, development and validation of alternative methods to animal testing.

TASCON GmbH

  • Internationally leading laboratory in the field of surface analysis, flexibly accredited testing laboratory (ISO/IEC 17025) as a partner for development and research.

nanoAnalytics GmbH

  • Analysis of surfaces and interfaces down to the micro- and nanometre range, consulting on questions for the fields of production, quality assurance, R&D; solutions for specific tasks in surface analytics.

BASF Coatings GmbH

  • Development, production and marketing of innovative solutions for automotive OEM and automotive refinish coatings.

OxProtect GmbH

  • Development of novel test methods and active substances between haemostasis and inflammation, applied research in these fields. Development of diagnostics, cooperation with pharmaceutical and technological partners.