Quantitative detection of nanoparticles in biological matrices is difficult, not least due to the large surface area of nanomaterials and the associated high reactivity. The small size of the materials contributes to their increased mobility and bioavailability. The aim of detecting nanoparticles in tissues using various techniques is to determine organ contamination as well as to detect and visualise the inhomogeneous distribution of nanoparticles and individual contaminated cells in the tissue. Research is constantly being conducted to improve the detection limit and the resolution of the detection methods.
Institute for Pharmaceutical and Medicinal Chemistry, WWU Münster
IPBP Institute for Pharmaceutical Biology and Phytochemistry, WWU Münster
SoN (Center for Soft Nanoscience), WWU Münster
Head of Biomedical Technology Centre, WWU Münster